We publish today in Nature the complete temporal series of transcription factors in the Drosophila medulla neuroblasts. We identify the genetic interactions between the temporal transcription factors (tTFs) that allow the series to progress. We show how the tTFs regulate neuronal identity transcription factors and identify the birth order and temporal window of origin for [...]
We publish today in Frontiers in Neuroscience a review discussing possible mechanisms for integration of spatial and temporal patterning that are often not coincident. Link
The Fly Cell Atlas was published today in Science. Our lab has contributed to this effort as part of the Fly Cell Atlas consortium.
Rebekah Rakotonirina-Ricquebourg joins the lab as an M2 from the Magistère Européen de Génétique at the University of Paris. Rebekah did her undergraduate studies at the University of Paris.
Elsa Iliopoulou joins the lab as an Ingénieur d'études. Elsa received her M.Sc. in Bioinformatics from the University of Crete where she studied the evolution of non-coding elements in teleost fish.
Nicola performed an in situ HCR against Hth in Drosophila L3 developing brains.
Konstantina's PhD paper is out today in Biology Open. They show that, in C. elegans, the combined action of multiple bHLH transcription factors is required to activate terminal selectors beyond a certain threshold that can then regulate downstream effector genes. Congratulations!
First lab meeting: things in the lab start to roll! In the meantime, the lab space has started to take shape. Can't wait for the first experiments!
Konstantina Filippopoulou is our first post-doc! She did her PhD at Institut de Biologie du Développement de Marseille in the lab of Vincent Bertrand studying mechanisms that ensure the robustness of neuronal specification.
We publish today in Developmental Biology a review introducing and summarizing all single-cell sequencing studies from the Drosophila visual system. We suggest ways to take full advantage of the available datasets. We discuss the state-of-the-art regarding neuronal identity regulation, neuronal circuit development and evolution of neuronal diversity. Link
