Marques et al describe the very first steps of neuronal maturation in the Drosophila central brain. They show that while ChAT (choline acetyltransferase) is transcribed very early, its translation is delayed and coordinated by the developmental stage of the animal. Link
We published today in Biorxiv the complete temporal series of transcription factors in the Drosophila medulla neuroblasts. We identify the genetic interactions between the temporal transcription factors (tTFs) that allow the series to progress. We show how the tTFs regulate neuronal identity transcription factors and describe the very first steps that a neuron takes to [...]
Nicola Grillenzoni is the Research Engineer in our lab. Prior to joining the lab he was a member of the Bassem Hassan lab at the Paris Brain Institute.
