Publications
2024
Konstantinides N., Desplan C. (2024) Neuronal circuit evolution: from development to structure and adaptive significance.
Cold Spring Harb Perspect Biol. doi: 10.1101/cshperspect.a041493 pdf
Ricquebourg R., Konstantinides N. (2024) Un mécanisme temporel pour la génération de la diversité neuronale.
Médecine Sciences (Paris) 40 : 251–257. doi: 10.1051/medsci/2024012 pdf2023
Filippopoulou K., Konstantinides N. (2023) Evolution of patterning.
The FEBS Journal 291(4):663-671. doi: 10.1111/febs.16995 pdf,,, , (2023) Asynchronous transcription and translation of neurotransmitter-related genes characterize the initial stages of neuronal maturation in Drosophila.
PLoS Biology 21(5):e3002115. pdf2022
Konstantinides N.$,*, Holguera I.$,Rossi A.M.$, Escobar A., Dudragne L., Chen Y.C., Tran T., Martinez Jaimes A., Özel M.N., Simon F., Shao Z., Tsankova N.M., Fullard J.F., Walldorf U., Roussos P., Desplan C.* (2022) A complete temporal transcription factor series in the fly visual system.
Nature 604: 316-322
$equal contribution * co-corresponding author pdfChen Y.C.*, Konstantinides N.* (2022) Integration of spatial and temporal patterning in the invertebrate and vertebrate nervous system.
Frontiers in Neuroscience 16: https://doi.org/10.3389/fnins.2022.854422
* co-corresponding author pdfLi H., Janssens J., De Waegeneer M., Kolluru S.S., Davie K., Gardeux V., Saelens W., David F., Brbić M., Leskovec J., McLaughlin C.N., Xie Q., Jones R.C., Brueckner K., Shim J., Tattikota S.G., Schnorrer F., Rust K., Nystul T.G., Carvalho-Santos Z., Ribeiro C., Pal S., Przytycka T.M., Allen A.M., Goodwin S.F., Berry C.W., Fuller M.T., White-Cooper H., Matunis E.L., DiNardo S., Galenza A., O’Brien L.E., Dow J.A.T., FCA Consortium, Jasper H., Oliver B., Perrimon N., Deplancke B., Quake S.R., Luo L., Aerts S. (2022) Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly.
Science 375(6584):eabk2432 pdf2021
Simon F.* and Konstantinides N.* (2021) Single-cell transcriptomics in the Drosophila visual system: advances and perspectives on cell identity regulation, connectivity, and neuronal diversity evolution.
Dev Biol 479:107-122
* co-corresponding author pdfÖzel M.N.$, Simon F.$, Jafari S., Holguera I., Chen Y.C, Benhra N., El-Danaf R.N., Kapuralin K., Malin J.A., Konstantinides N.*, Desplan C.* (2021) Neuronal diversity and convergence in a visual system developmental atlas.
Nature 589(7840):88-95
* co-corresponding author pdfOpachaloemphan C.$, Mancini M.$, Konstantinides N.$, Parikh A., Mlejnek J., Yan H., Reinberg D., Desplan C. (2021) Early behavioral and molecular events leading to caste switching in the ant Harpegnathos.
Genes and Development 35: 410-424.
$equal contribution pdf2020
Konstantinides N.*, and Desplan C.* (2020) Neuronal differentiation strategies: insights from single-cell sequencing and machine learning.
Development 147: dev193631
* co-corresponding author pdf2018
Konstantinides N.*$, Kapuralin K.$, Fadil C., Barboza L., Satija R., Desplan C.* (2018) Phenotypic convergence in the brain: distinct transcription factors regulate common terminal neuronal characters.
Cell 174(3):622-635.
$equal contribution * co-corresponding author pdfDavie K., Janssens J., Koldere D., De Waegeneer M., Pech U., Kreft L., Aibar S., Makhzami S., Christiaens V., Bravo González-Blas C., Poovathingal S., Hulselmans G., Spanier K.I., Moerman T., Vanspauwen B., Geurs S., Voet T., Lammertyn J., Thienpont B., Liu S., Konstantinides N., Fiers M., Verstreken P., and Aerts S. (2018) A single-cell transcriptome atlas of the ageing Drosophila brain. Cell 174(4):982-998. pdf
Konstantinides N.*, Degabriel S., Desplan C. (2018) Neuro-evo-devo in the single cell sequencing era.
Curr Opin Syst Biol 11:32-40.
* corresponding author pdf2017
Perry M., Konstantinides N., Pinto-Teixeira F., Desplan C. (2017) Generation and evolution of neural cell types and circuits: insights from the Drosophila visual system.
Annu Rev Genet. 51:501-527 pdf2016
Grillo M.*, Konstantinides N.*, Averof M.* (2016) Old questions, new models: unraveling complex organ regeneration with new experimental approaches.
Curr Opin Genet Dev. 40:23-31.
* co-corresponding author pdfPinto-Teixeira F.$, Konstantinides N.*$, Desplan C. (2016) Programmed cell death acts at different stages of Drosophila neurodevelopment to shape the central nervous system.
FEBS Lett. 590(15):2435-53
$ equal contribution* co-corresponding author pdfKao D., Lai A.G., Stamataki E., Rosic S., Konstantinides N., et al. (2016) The genome of the crustacean Parhyale hawaiensis: a model for animal development, regeneration, immunity and lignocellulose digestion.
Elife. 5. pii: e20062 pdfKonstantinides N. A mathematical approach for secondary structure analysis can provide an eyehole to the RNA world.
Biorxiv doi: https://doi.org/10.1101/079608 pdf2015
Konstantinides N., Rossi A.M. and Desplan C. (2015) Common temporal identity factors regulate neuronal diversity in fly ventral nerve cord and mouse retina.
Neuron 85(3):447-9 pdfCourgeon M., Konstantinides N. and Desplan C. (2015) Cell competition: dying for communal interest.
Current Biology 25(8):R339-41 pdf2014
Konstantinides N.* and Averof M.* (2014) A common cellular basis for muscle regeneration in arthropods and vertebrates.
Science 343(6172):788-91
* co-corresponding author pdf2011
Kontarakis Z., Pavlopoulos A., Kiupakis A., Konstantinides N., Douris V. and Averof M. (2011) A versatile strategy for gene trapping and trap conversion in emerging model organisms.
Development 138(12):2625-30 pdfKontarakis Z., Konstantinides N., Pavlopoulos A. and Averof M. (2011) Reconfiguring gene traps for new tasks using iTRAC.
Fly 5(4) pdfBirk UJ, Darrell A., Konstantinides N., Sarasa-Renedo A. and Ripoll J. (2011) Improved reconstructions and generalized filtered back projection for Optical Projection Tomography.
Appl Opt 50(4):392-8 pdf2010
Birk UJ, Rieckher A., Konstantinides N., Darrell A., Sarasa-Renedo A., Meyer H., Tavernarakis N., and Ripoll J. (2010) Correction for specimen movement and rotation errors for in-vivo Optical Projection Tomography.
Biomed Opt Expr 1(1):87–96 pdf