Publications

  • 2022

    Cheng Y.C.*, Konstantinides N.* (2022) Integration of spatial and temporal patterning in the invertebrate and vertebrate nervous system.
    Frontiers in Neuroscience 16: https://doi.org/10.3389/fnins.2022.854422
    * co-corresponding author pdf

    Li H., Janssens J., De Waegeneer M., Kolluru S.S., Davie K., Gardeux V., Saelens W., David F., Brbić M., Leskovec J., McLaughlin C.N., Xie Q., Jones R.C., Brueckner K., Shim J., Tattikota S.G., Schnorrer F., Rust K., Nystul T.G., Carvalho-Santos Z., Ribeiro C., Pal S., Przytycka T.M., Allen A.M., Goodwin S.F., Berry C.W., Fuller M.T., White-Cooper H., Matunis E.L., DiNardo S., Galenza A., O’Brien L.E., Dow J.A.T., FCA Consortium, Jasper H., Oliver B., Perrimon N., Deplancke B., Quake S.R., Luo L., Aerts S. (2022) Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly.
    Science 375(6584):eabk2432 pdf

  • 2021

    Konstantinides N.$,*, Rossi A.M.$, Escobar A., Dudragne L., Chen Y.C., Tran T., Martinez Jaimes A., Özel M.N., Simon F., Shao Z., Tsankova N.M., Fullard J.F., Walldorf U., Roussos P., Desplan C.* (2021) A comprehensive series of temporal transcription factors in the fly visual system.
    Biorxiv doi: https://doi.org/10.1101/2021.06.13.448242
    $equal contribution * co-corresponding author pdf

    Simon F.* and Konstantinides N.* (2021) Single-cell transcriptomics in the Drosophila visual system: advances and perspectives on cell identity regulation, connectivity, and neuronal diversity evolution.
    Dev Biol 479:107-122
    * co-corresponding author pdf

    Marques G.S., Teles-Reis J., Konstantinides N., Brito P.H., Homem C.C.F. (2021) Fate transitions in Drosophila neural lineages: a single cell road map to mature neurons.
    Biorxiv doi: https://doi.org/10.1101/2021.06.22.449317 pdf

    Özel M.N.$, Simon F.$, Jafari S., Holguera I., Chen Y.C, Benhra N., El-Danaf R.N., Kapuralin K.,  Malin J.A., Konstantinides N.*, Desplan C.* (2021) Transient and heterogeneous neuronal types revealed by a comprehensive developmental atlas of the Drosophila optic lobe.
    Nature 589(7840):88-95
    * co-corresponding author pdf

    Opachaloemphan C.$, Mancini M.$, Konstantinides N.$, Parikh A., Mlejnek J., Yan H., Reinberg D., Desplan C. (2021) Early behavioral and molecular events leading to caste switching in the ant Harpegnathos.
    Genes and Development 35: 410-424.
    $equal contribution pdf

  • 2020 

    Konstantinides N.*, and Desplan C.* (2020) Neuronal differentiation strategies: insights from single-cell sequencing and machine learning.
    Development 147: dev193631
    * co-corresponding author pdf

  • 2018

    Konstantinides N.*$, Kapuralin K.$, Fadil C., Barboza L., Satija R., Desplan C.* (2018) Phenotypic convergence in the brain: distinct transcription factors regulate common terminal neuronal characters.
    Cell 174(3):622-635.
    $equal contribution * co-corresponding author pdf

    Davie K., Janssens J., Koldere D., De Waegeneer M., Pech U., Kreft L., Aibar S., Makhzami S., Christiaens V., Bravo González-Blas C., Poovathingal S., Hulselmans G., Spanier K.I., Moerman T., Vanspauwen B., Geurs S., Voet T., Lammertyn J., Thienpont B., Liu S., Konstantinides N., Fiers M., Verstreken P., and Aerts S. (2018) A single-cell transcriptome atlas of the ageing Drosophila brain. Cell 174(4):982-998. pdf

    Konstantinides N.*, Degabriel S., Desplan C. (2018) Neuro-evo-devo in the single cell sequencing era.
    Curr Opin Syst Biol 11:32-40.
    * corresponding author pdf

  • 2017

    Perry M., Konstantinides N., Pinto-Teixeira F., Desplan C. (2017) Generation and evolution of neural cell types and circuits: insights from the Drosophila visual system.
    Annu Rev Genet. 51:501-527 pdf

  • 2016

    Grillo M.*, Konstantinides N.*, Averof M.* (2016) Old questions, new models: unraveling complex organ regeneration with new experimental approaches.
    Curr Opin Genet Dev. 40:23-31.
    * co-corresponding author  pdf

    Pinto-Teixeira F.$, Konstantinides N.*$, Desplan C. (2016) Programmed cell death acts at different stages of Drosophila neurodevelopment to shape the central nervous system.
    FEBS Lett. 590(15):2435-53
    $ equal contribution* co-corresponding author pdf

    Kao D., Lai A.G., Stamataki E., Rosic S., Konstantinides N., et al. (2016) The genome of the crustacean Parhyale hawaiensis: a model for animal development, regeneration, immunity and lignocellulose digestion.
    Elife. 5. pii: e20062 pdf

    Konstantinides N. A mathematical approach for secondary structure analysis can provide an eyehole to the RNA world.
    Biorxiv doi: https://doi.org/10.1101/079608 pdf

  • 2015

    Konstantinides N., Rossi A.M. and Desplan C. (2015) Common temporal identity factors regulate neuronal diversity in fly ventral nerve cord and mouse retina.
    Neuron 85(3):447-9 pdf

    Courgeon M., Konstantinides N. and Desplan C. (2015) Cell competition: dying for communal interest.
    Current Biology 25(8):R339-41 pdf

  • 2014

    Konstantinides N.* and Averof M.* (2014) A common cellular basis for muscle regeneration in arthropods and vertebrates.
    Science 343(6172):788-91
    * co-corresponding author pdf

  • 2011

    Kontarakis Z., Pavlopoulos A., Kiupakis A., Konstantinides N., Douris V. and Averof M. (2011) A versatile strategy for gene trapping and trap conversion in emerging model organisms.
    Development 138(12):2625-30 pdf

    Kontarakis Z., Konstantinides N., Pavlopoulos A. and Averof M. (2011) Reconfiguring gene traps for new tasks using iTRAC.
    Fly 5(4) pdf

    Birk UJ, Darrell A., Konstantinides N., Sarasa-Renedo A. and Ripoll J. (2011) Improved reconstructions and generalized filtered back projection for Optical Projection Tomography.
    Appl Opt 50(4):392-8 pdf

  • 2010

    Birk UJ, Rieckher A., Konstantinides N., Darrell A., Sarasa-Renedo A., Meyer H., Tavernarakis N., and Ripoll J. (2010) Correction for specimen movement and rotation errors for in-vivo Optical Projection Tomography.
    Biomed Opt Expr 1(1):87–96 pdf